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Research proves that the use of the whole herb will achieve greater results than only using part of the herb
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extractions can be made acidic (pH 9.5) with 1-N hydrochloric acid, filtered and
washed in a separatory funnel or improvised siphon-jug apparatus with diethyl
ether, neutralized with ammonium hydroxide and evaporated to dryness.
However, most of these solvents are difficult for the non-professional to obtain.
Perhaps it is just as well since many of these solvents are either toxic or
explosive if handled improperly. Also, we do not always know precisely what we
are trying to extract. Some of the active principles may be non-alkaloidal. Too
much purification might remove some of the active substances. The approach
given here employs materials which may be purchased inexpensively at any
supermarket and are safe to work with. This procedure extracts all of the alcohol
and water-soluable alkaloids and non-alkaloidal materials and permits only the
fibrous pulp to be discarded.
Pulverize the dried cactus (tufts and spines need not be removed). Prepare a
mixture of two parts isopropyl rubbing alcohol and one part clear, non-sudsing,
unscented and untinted ammonia. Make the pulverized material soggy with this
mixture and allow it to stand covered overnight. Do not use aluminum or iron
wares during any of these steps. After soaking, cover the mash with isopropyl
alcohol and boil in a heat bath for six hours. Strain the liquids through muslin and
press as much liquid as possible from the pulp. With fresh alcohol repeat the
boiling and straining three more times. Combine the strained liquids. Evaporate
this in a heat bath until only a tar remains. (When evaporating a solvent use and
electric range or hot plate rather than a gas stove. Have adequate ventilation and
avoid breathing the fumes.) The tar can be further dried by spreading it thinly on
a baking tray and placing it in an oven set at the lowest possible heat. Remove
the tray once every fifteen minutes to examine the material. When it appears to
be almost dry place it back in the oven, shut the heat off, and let it stay there until
the oven cools.
DICTIONARY OF CACTUS ALKALOIDS
• Anhalidine: Tetrahydroisoquinoline alkaloid (2-methyl-6,7-dimeethoxy-8-
hydroxy-1,2,3,4,-tetrahydroisoquinoline) Found in Lophophora and
• B-O-methylsynephrine: Phenolic B-phenethylamine found in citrus trees
and some cacti. No data on pharmacology, but similar compound B-Omethylepin-
ephrine produces considerable CNS stimulation.
• 3-dimethyltrichocereine: B-phenethylamine alkaloid (N,N-dimethyl-3-
hydroxy-4,5-dimethoxy-B-phenethylamine). Found in Pelecyphora and
some Trichocereus species.
• Dolichotheline: Imidazole alkaloid properly known as N-isovalerylhistamine
or 4(5)-2-N-isovalerylaminoethylimidazole. Found only in Dolichothele
and Gymnocactus species. Pharmacological action still unknown.
• Homoveratrilamine: a dimethoxy form of the mescaline molecule (3,4-
dimethoxy-B-phenethylamine). It has no activity by itself, but may alter the
mescaline experience s
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There is no longer an illegal drug industry, for the penalties are severe and there is no real demand as people have learnt to respect the culture and ritual of their home grown psychotropic plants
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