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erature reading lesson to those who
have made these claims. See Proceedings of the Royal Society of
London, Series B, Volume 155, pages 26 to 54 (1961). Also see US
Patent 3,219,545. You will note while reading these articles detailing
how to get lysergic amide production in a culture medium that these
guys had to scour the globe to find that rare strain of claviceps fungus
that will cooperate in this manner. The vast majority of claviceps
fungi just will not produce these alkaloids while being cultured. See
the following articles to convince yourself of just how futile it is to
collect a wild strain of claviceps and try to get it to produce lysergic
acid amides in culture: Ann. Rep. Takeda Res. Lab Volume 10, page 73
(1951); and Farmco, Volume 1, page 1 (1946); also Arch. Pharm. Berl.
Volume 273, page 348 (1935); also American Journal of
Practical LSD Manufacture
Botany, Volume 18, page 50 (1931); also Journal of the American
Pharmacy Association Volume 40, page 434 (1951); also US patent
2,809,920; also Canadian Journal of Microbiology, Volume 3, page
55 (1957), and Volume 4, page 611 (1958) and Volume 6, page 355
(1960); also Journal of the American Pharmacy Society Volume 44,
page 736 (1955).
With this matter disposed of, it is time to move on to what
actually are viable sources of lysergic acid amides for the production of
LSD. This is the farming end of the acid business. It is only through
raising ergot-infested rye, or growing morning glories and Hawaiian
baby woodrose that the required feedstocks of lysergic compounds
can be obtained without making a target of oneself. I have for years
seen ads in High Times offering morning glory seeds and Hawaiian
baby woodrose seeds for sale, but these are offered in small amounts at
high prices. I would bet my bottom dollar that these outfits, if they are
not front operations, will at least report to the heat any large orders they
get. To avoid detection, the aspiring LSD manufacturer must be ready
to get his hands dirty, and spend some time as a farmer.
The most difficult farming choice, and as luck would have it, the
one that gives the purest acid, is to grow a patch of ergot-infested rye.
The reason why ergot is superior to growing morning glory seeds or
woodrose seeds is that these seeds have a considerable amount of
another type of alkaloid in them besides the ones that yield lysergic
acid. These other alkaloids are of the clavine type, meaning that they
have the lysergic-acid skeleton, but lack the carboxyl grouping. In its
place will be a methyl grouping, an alcohol grouping, a methyl
alcohol grouping or combinations of the above. These clavine
alkaloids will likely be carried all the way through into the product,
producing both the GIGO situation during the synthetic operations
and a contaminated product when finished. I will present my ideas on
how to remove them, but they are best avoided in the first place.
Ergot is the name given to a dark brow
San Pedro Seeds For Sale How To Enhance Shroom Effects
Mimosa Hostilis Extraction Kits The
extractions can be made acidic (pH 9.5) with 1-N hydrochloric acid, filtered and
washed in a separatory funnel or improvised siphon-jug apparatus with diethyl
ether, neutralized with ammonium hydroxide and evaporated to dryness.
However, most of these solvents are difficult for the non-professional to obtain.
Perhaps it is just as well since many of these solvents are either toxic or
explosive if handled improperly. Also, we do not always know precisely what we
are trying to extract. Some of the active principles may be non-alkaloidal. Too
much purification might remove some of the active substances. The approach
given here employs materials which may be purchased inexpensively at any
supermarket and are safe to work with. This procedure extracts all of the alcohol
and water-soluable alkaloids and non-alkaloidal materials and permits only the
fibrous pulp to be discarded.
Pulverize the dried cactus (tufts and spines need not be removed). Prepare a
mixture of two parts isopropyl rubbing alcohol and one part clear, non-sudsing,
unscented and untinted ammonia. Make the pulverized material soggy with this
mixture and allow it to stand covered overnight. Do not use aluminum or iron
wares during any of these steps. After soaking, cover the mash with isopropyl
alcohol and boil in a heat bath for six hours. Strain the liquids through muslin and
press as much liquid as possible from the pulp. With fresh alcohol repeat the
boiling and straining three more times. Combine the strained liquids. Evaporate
this in a heat bath until only a tar remains. (When evaporating a solvent use and
electric range or hot plate rather than a gas stove. Have adequate ventilation and
avoid breathing the fumes.) The tar can be further dried by spreading it thinly on
a baking tray and placing it in an oven set at the lowest possible heat. Remove
the tray once every fifteen minutes to examine the material. When it appears to
be almost dry place it back in the oven, shut the heat off, and let it stay there until
the oven cools.
DICTIONARY OF CACTUS ALKALOIDS
• Anhalidine: Tetrahydroisoquinoline alkaloid (2-methyl-6,7-dimeethoxy-8-
hydroxy-1,2,3,4,-tetrahydroisoquinoline) Found in Lophophora and
• B-O-methylsynephrine: Phenolic B-phenethylamine found in citrus trees
and some cacti. No data on pharmacology, but similar compound B-Omethylepin-
ephrine produces considerable CNS stimulation.
• 3-dimethyltrichocereine: B-phenethylamine alkaloid (N,N-dimethyl-3-
hydroxy-4,5-dimethoxy-B-phenethylamine). Found in Pelecyphora and
some Trichocereus species.
• Dolichotheline: Imidazole alkaloid properly known as N-isovalerylhistamine
or 4(5)-2-N-isovalerylaminoethylimidazole. Found only in Dolichothele
and Gymnocactus species. Pharmacological action still unknown.
• Homoveratrilamine: a dimethoxy form of the mescaline molecule (3,4-
dimethoxy-B-phenethylamine). It has no activity by itself, but may alter the
mescaline experience s
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there is decent drainage.
Cacti tend to grow mostly during spring and autumn, to send down roots in the
summer, and to rest through winter. Although cactus cuttings may be planted
anytime of the year they stand the best chance if planted in the late spring. They
should be watered thoroughly once or twice a week depending upon how rapidly
moisture is lost. The soil an inch below the surface should always contain some
moisture. Watering can be cut back to less than half during the winter.
INCREASING THE POTENCY OF PSYCHOACTIVE CACTI There are several
factors which influence production of mescaline and related alkaloids in cacti.
Presence of a wide variety of trace minerals is important. Occasional watering
with Hoagland A-Z trace mineral concentrate provides these minerals. Combine
1 part concentrate with 9 parts water and water cacti with this once every two
Experiments conducted by Rosenberg, Mclaughlin and Paul at the University of
of Michigan, Ann Arbor in 1966 demonstrated that dopamine is a precursor of
mescaline in the peyote cactus. Tyramine and dopa were also found to be
mescaline precursors, but not as immediate and efficient as dopamine. It
appears that in the plant tyosine breaks down to become tyramine and dopa.
These then recombine to form dopamine which is converted to nor-mescaline
and finally to mescaline. One can take advantage to this sequence by inject-ing
each peyote plant with dopamine 4 weeks prior to harvesting. Much of the
dopamine will convert to mescaline during this time, giving a considerable
increase in the alkaloid of the plant. Prepare a saturated solution of free base
dopamine in a .05 N solution of hydrochloric acid and inject 1-2 cc into the root of
each plant and the same amount into the green portion above the root. Let the
needle penetrate to the center of the plant, inject slowly and allow the needle to
remain in place a few seconds after injection. It is best to deprive the plant of
water for 1-2 weeks before injection. This makes the plant tissues take up the
injection fluids more readily. If dopamine is not available, a mixture of tyramine
and dopa can be used instead 6 weeks before harvesting for comparable results.
San Pedro and other mescaline-bearing cacti can be similarly treated for
increased mescaline production. Inject at the base of the plant and again every
3-4 inches following a spiral pattern up the length of the plant. A series of booster
injections can be given to any of these cacti every 6-8 weeks and once again 4
weeks before harvesting for greater mescaline accumulation.
It is also possible to increase the macromerine and nor-macromerine content of
Doñana cacti using tyramine or DL-norepinephrine as precursors. Injections
should be given 20-25 days before harvesting. Series of injections can be given
45 days apart for higher alkaloid accumulation.
EXTRACTING PURE MESCALINE FROM PEYOTE OR SAN PEDRO
The isolation of mescaline from cacti
phenylethylamine erowid How To Enhance Shroom Effects Sceletiumtortuosum
Alkaline Spiriual Drugs eaching.
Often there are reports of blue glows and jaguars, a holy animal
in many endogenous South American cultures. I have been told that
McKenna reports that eskimos given an ayahuasca type potion
reported seeing large cats, which, of course, are not arctic
animals. I however, have found (from admittedly little reading)
McKenna's work to be questionable and less than scientific.
However, his reports often do parallel others.
MAOIs are a class of drugs that all do the same thing:
prevent the destruction of monoamines (like DMT). One MAOI is
harmaline. Harmaline is easily obtained. Syrian rue is an
excellent source. Three grams of seed, extracted with the DMT or
eaten alone should suffice. Harmaline containing plants can also
be smoked for a more rapid onset. Doses over three grams do not
add more potency. Caution should be used with MAOIs. Large doses
are hallucinogenic in and of themselves. Large doses are
unpleasant and sometimes fatal.
The remainder of this section is information cited directly
file:///C|/Documents%20and%20Settings/All%20Users/...0Culture/Ayahuasca%20and%20DMT/DMT%20FAQ%202.0.txt (3 of 13)4/14/2004 9:11:34 PM
from "Legal Highs" by Twentieth Century Alchemists. They just did
a better job than I could do. I have seen this posted around the
net and is highly recommended. This information pertains to
precautions for MAO inhibitors. READ THEM, KNOW THEM ! You will
notice several discrepancies: Legal Highs says that MAOI and
mescaline combinations are very dangerous, which contradicts
Ott's later reports on the subject. Legal Highs suggests that 5-
Me-DMT is a MAOI, which I cannot substantiate. This would render
P. tuberosa psychoactive alone. I cannot substantiate this
READ THIS!! VERY IMPORTANT. IGNORING THIS COULD LEAD TO SERIOUS
MEDICAL PROBLEMS (like death...)
Unless one is very experienced in pharmacology it is
unwise to experiment with combinations of drugs. Even when using
a single drug, thought should be given to all substances, both
food and drug, which have been taken recently. Most primitive
people fast or at least abstain from certain substances for
several days prior to taking a sacrament. Substances most
universally avoided are alcohol, coffee, meat, fat and salt. Some
drugs potentiate others. For example, atropine will increase the
potency of mescaline, harmine, cannabis and opiates. Many of the
substances discussed in this book are MAO inhibitors. MAO
(monoamine oxidase) is an enzyme produced in the body which
breaks down amines and renders them harmless and ineffective. A
MAO inhibitors interfere with the protective enzyme and leaves
the body vulnerable to these amines. A common substance such as
tyramine, which is usually metabolized with l
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