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“CHACRUNA” Dried Whole Leaf (Psycotria viridis)
e mental discipline. People who cannot endure the
bitterness of peyote often go to various extremes to get it into the system without
having to taste it. One fairly effective method is to drink unsweetened grapefruit
juice while chewing it. The acids in the juice somewhat neutralize some of the
bitter bases. Another method is to grind the dried buttons in a pepper grinder and
pack the pulverised material into OOO capsules which are washed down with
warm water. This is an effective method but it can take 20 capsules or more to
get a 350mg dose of mescaline. Often people will boil the buttons in water for
several hours to make a concentrated tea. A cup of this decoction can be
swallowed in a few hasty gulps. Another preparation that is occasionally used is
a jello-type dessert made with the fresh or dried plant. If spoonfulls are
swallowed whole the gelatine serves as a sort of shield protecting the tastebuds
from contact with the bitter material. It also slows down the the absorption of the
drug in the digestive tract. This can be of value. It is generally recommended that
anyone consuming peyote or mescaline ingest it gradually during a period of an
hour or take two half doses 45 minutes apart. This is done to reduce the shock of
the alkaloid to the system. Nausea or queasiness is sometimes experienced half
an hour or so after taking peyote or mescaline. This usually passes in less than
an hour. A sip of grapefruit juice will sometimes dispel the sick feeling. During the
peyote ceremony Indians encourage vomiting rather than restraint if the urge
presents itself. Throwing up, they believe, is apurging of both physical and
spiritual ills. Most tribes fast for at least a day before taking peyote. This can also
help to minimize gastric distress. One should not have eaten for at least 6 hours
before taking either mescaline or peyote.
A method which avoids both the bitterness and the nausea is the rectal infusion.
8-16 grams of dried peyote is ground into a fine powder and boiled in a pint of
water for 30 minutes. It is then strained and further boiled to reduce it's volume to
one half pint. After cooling, this is taken as an enema using a small bulb syringe
and retained for at least two hours. If there is any fecal matter in the lower bowel,
a small cleansing enema should be taken and thoroughly expelled before having
the peyote infusion. Otherwise much of the drug will be taken up by the feces
and later voided.
FINDING AND PICKING PEYOTE
The peyote cactus may be found in many areas throughout the Chihuahuan
Desert from central Mexico to southern Texas. When a site is found where
peyote grows it usually does so in abundance. Sometimes it grows in open sunlit
places, but more often it is found in clusters under fairly large shrubs, among
mesquite or creosote bushes or in the shade of large succulents.
The best time to harvest any cactus is after a long dry spell. The worst time is
during or after a rainy period.
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Cacti tend to grow mostly during spring and autumn, to send down roots in the
summer, and to rest through winter. Although cactus cuttings may be planted
anytime of the year they stand the best chance if planted in the late spring. They
should be watered thoroughly once or twice a week depending upon how rapidly
moisture is lost. The soil an inch below the surface should always contain some
moisture. Watering can be cut back to less than half during the winter.
INCREASING THE POTENCY OF PSYCHOACTIVE CACTI There are several
factors which influence production of mescaline and related alkaloids in cacti.
Presence of a wide variety of trace minerals is important. Occasional watering
with Hoagland A-Z trace mineral concentrate provides these minerals. Combine
1 part concentrate with 9 parts water and water cacti with this once every two
Experiments conducted by Rosenberg, Mclaughlin and Paul at the University of
of Michigan, Ann Arbor in 1966 demonstrated that dopamine is a precursor of
mescaline in the peyote cactus. Tyramine and dopa were also found to be
mescaline precursors, but not as immediate and efficient as dopamine. It
appears that in the plant tyosine breaks down to become tyramine and dopa.
These then recombine to form dopamine which is converted to nor-mescaline
and finally to mescaline. One can take advantage to this sequence by inject-ing
each peyote plant with dopamine 4 weeks prior to harvesting. Much of the
dopamine will convert to mescaline during this time, giving a considerable
increase in the alkaloid of the plant. Prepare a saturated solution of free base
dopamine in a .05 N solution of hydrochloric acid and inject 1-2 cc into the root of
each plant and the same amount into the green portion above the root. Let the
needle penetrate to the center of the plant, inject slowly and allow the needle to
remain in place a few seconds after injection. It is best to deprive the plant of
water for 1-2 weeks before injection. This makes the plant tissues take up the
injection fluids more readily. If dopamine is not available, a mixture of tyramine
and dopa can be used instead 6 weeks before harvesting for comparable results.
San Pedro and other mescaline-bearing cacti can be similarly treated for
increased mescaline production. Inject at the base of the plant and again every
3-4 inches following a spiral pattern up the length of the plant. A series of booster
injections can be given to any of these cacti every 6-8 weeks and once again 4
weeks before harvesting for greater mescaline accumulation.
It is also possible to increase the macromerine and nor-macromerine content of
Doñana cacti using tyramine or DL-norepinephrine as precursors. Injections
should be given 20-25 days before harvesting. Series of injections can be given
45 days apart for higher alkaloid accumulation.
EXTRACTING PURE MESCALINE FROM PEYOTE OR SAN PEDRO
The isolation of mescaline from cacti
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@Tuesday, September 25, 2018 5:29:21 PM