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OTHELE: Several tribes occasionally use any one of several species of
Dolichothele as a peyote-like sacrament. These include D. baumii, D.
longimamma, D. melalenca, D. sphaerica. D. surculosa, and D. uberiforma.
Recent investigations have revealed in these the presence of small amounts of
the alkaloids N-methylphenethylamine, B-O-methylsynephrine, Nmethyltryamine,
synephrine, hordenine, and dolichotheline (Nisovalerylhistamine).
MISCELLANEOUS: Several other cacti have been used by the Tarahumares as
peyote substitutes. Among these are Obregonia denegrii, Aztekium ritterii,
Astrophytum asterias, A. capricorne, A. myriostigma (Bishops cap), and Solisia
pectinata. The Tarahumares also consume a cactus which they call Mulato
(Mammillaria micromeris) and claim that it prolongs life, gives speed to runners,
and clarifies vison for mystical insights. Another cactus similarly employed is
known as Rosapara (Epitheliantha micromeris) is believed by many botanists to
be the same species as Mulato, but at a later vegetative stage. The large cactus
Pachycereus pecten-aboriginum, known locally as Cawe, has occasionally been
used as a narcotic.
What little studies have been carried out on these cacti have revealed the
presence of alkaloids most of the other species we have discussed, but no
mescaline or macromerine. Many of these alkaloids have some
psychopharmacalogical properties, but nothing to compare with those two drugs.
Furthermore, the amounts of these alkaloids are usually so small as to be
insignificant. For example, the species Obregonia denegrii contains tyramine
0.003 percent, hordenine 0.002 percent, and N-methyltyramin 0.0002 percent.
These are all known sympathomimetics, but the percentages are far too minute
to have any value. Several publications in recent years have mentioned the
sacramental use of these cacti. As a result thousands of people have obtained
these plants from cactus dealers and ingested them, usually with disappointing
(and sometimes nauseating) results. Sadly many of these cacti are quite rare. If
too many people destroy them experimentally, they may become a seriously
endangered species. The most suitable cacti for a true psychedelic experience
are peyote, which is for the most part illegal, and several species of Trichocereus
(such as San Pedro), which are still legal.
SAN PEDRO: This cactus has gained considerable fame in the past five years
after numerous reports that it is hallucinogenic, contains mescaline, and is readily
available from cactus nurseries. This plant known botanically as Trichocereus
pachanoi, is native to the Andes of Peru and Equador. Unlike the small peyote
cactus, San Pedro is large and multi-branched. In it's natural enviorment, it often
grows to heights of 10 or 15 feet. It's mescaline content is less than that of
peyote (0.3 - 1.2 percent), but because of it's great size and rapid growth, it may
provide a more economical source of mescaline than peyote. One pla
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tina party drig the empty jug with 100 ml of ether to salvage
any crystals in the jug and pour the ether over the crystals in the filter. After the
ether has passed through the filter repeat the rinsing with another 100 ml of
ether. Then let the crystals dry. If ether is not available or you do not wish to use
such a highly combustible substance, the precipitate and residual benzene can
be poured into a beaker. The jug should be rinsed several more times with a little
benzene and added to the beaker so no crystals are left behind. The beaker is
then placed in a heat bath until all of the benzene has been evaporated.
The next step is to purify the mescaline sulfate crystals. Dissolve the dry crystals
in 200 ml of near-boiling distilled water. Add a pinch of activated charcoal (Norite)
and filter while still hot through number 2 filter paper. The hot water which
contains the mescaline will pass through the filter. The Norite absorbes impurities
from the mescaline. After the liquids have passed through the filter pour a little
more hot water over the filter to rinse through any remaining mescaline which
may have impregnated the filter paper. Add 10 percent ammonia solution a few
drops at a time to the hot filtrates until the solution registers between pH 6.5 and
Place a boiling stone in the solution Mestizomushroomstrain and reduce it's volume to 75 ml by boiling.
Remove the boiling stone and allow the solution to cool to room temperature.
Place the solution in a freezer or in a refrigerator set to the coldest possible
temperature and allow the solution to cool to almost freezing. Tiny white needlelike
crystals form around the bottom and sides of the beaker. Break up the
crystals with a glass stirring rod while the solution is still ice cold and pour
through a filter. Mescaline sulfate is insoluable in near freezing water and will not
pass through the filter.
Rinse the beaker with fresh ice water and pour this over
the filter. The crystals will now be pure white and can be dried under a heat lamp
or in an over at 250 degrees F. More mescaline can be salvaged from the water
that has passed through the filter by boiling these liquids down to about 20 ml,
adding Norite while hot, filtering through number 2 paper as before, chilling the
filterate to near freezing as once before, filtering while cold, rinsing with ice water
and drying the crystals. This repetition should obtain at least two more grams of
If large volume mescaline extraction is being conducted it
would be worthwhile to repeat this salvaging procedure several more times.
MIXED ALKALOID EXTRACTIONS
There are numerous methods for extracting a mixture of the alkaloids from cacti.
Different methods may result in varying degrees of purity. For example, the dried,
pulverized material can be defatted with petroleum ether or lighter fluid prior to
extraction to remove lipid content; solvent combinations such as
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