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there is decent drainage. Cacti tend to grow mostly during spring and autumn, to send down roots in the summer, and to rest through winter. Although cactus cuttings may be planted anytime of the year they stand the best chance if planted in the late spring. They should be watered thoroughly once or twice a week depending upon how rapidly moisture is lost. The soil an inch below the surface should always contain some moisture. Watering can be cut back to less than half during the winter. INCREASING THE POTENCY OF PSYCHOACTIVE CACTI There are several factors which influence production of mescaline and related alkaloids in cacti. Presence of a wide variety of trace minerals is important. Occasional watering with Hoagland A-Z trace mineral concentrate provides these minerals. Combine 1 part concentrate with 9 parts water and water cacti with this once every two months. Experiments conducted by Rosenberg, Mclaughlin and Paul at the University of of Michigan, Ann Arbor in 1966 demonstrated that dopamine is a precursor of mescaline in the peyote cactus. Tyramine and dopa were also found to be mescaline precursors, but not as immediate and efficient as dopamine. It appears that in the plant tyosine breaks down to become tyramine and dopa. These then recombine to form dopamine which is converted to nor-mescaline and finally to mescaline. One can take advantage to this sequence by inject-ing each peyote plant with dopamine 4 weeks prior to harvesting. Much of the dopamine will convert to mescaline during this time, giving a considerable increase in the alkaloid of the plant. Prepare a saturated solution of free base dopamine in a .05 N solution of hydrochloric acid and inject 1-2 cc into the root of each plant and the same amount into the green portion above the root. Let the needle penetrate to the center of the plant, inject slowly and allow the needle to remain in place a few seconds after injection. It is best to deprive the plant of water for 1-2 weeks before injection. This makes the plant tissues take up the injection fluids more readily. If dopamine is not available, a mixture of tyramine and dopa can be used instead 6 weeks before harvesting for comparable results. San Pedro and other mescaline-bearing cacti can be similarly treated for increased mescaline production. Inject at the base of the plant and again every 3-4 inches following a spiral pattern up the length of the plant. A series of booster injections can be given to any of these cacti every 6-8 weeks and once again 4 weeks before harvesting for greater mescaline accumulation. It is also possible to increase the macromerine and nor-macromerine content of Doñana cacti using tyramine or DL-norepinephrine as precursors. Injections should be given 20-25 days before harvesting. Series of injections can be given 45 days apart for higher alkaloid accumulation. EXTRACTING PURE MESCALINE FROM PEYOTE OR SAN PEDRO CACTUS The isolation of mescaline from cacti Peruvian Torch Skin Cuts (Trichocereus Peruvianus) – Very strong Contact Chat Contact Plant trees San Pedro Cactus (Trichocereus pachanoi)De-cored Dried Outer Skin Contact Chat Terscheckii Cactus Skin Cuts (Trichocereus Terscheckii)

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ydrolysed ergot alkaloids, to unreacted lysergic acid, or lysergic acid hydrazides to iso- LSD and God knows what substances created by the mishandling of the raw materials and product, a contaminated product is much easier to make than a pure one. The use of large volumes of solvents poses twin problems: obtaining them and disposing of them. Both problems are made vastly Practical LSD Manufacture 70 simpler by recycling the solvents. Just because a solvent has been used once in a given stage of the process does not mean its useful lifetime is over. For example, the solvent used for defatting the crop is easily made as good as new by distilling it to free it of its load of fat. Other solvents are not so easily recovered for re-use because the procedure calls for the given solvent to be removed from the product by vacuum evaporation. In this case, the solvent can be collected in a cold trap placed along the vacuum line on its way to the vacuum source. If a pump is used to create the vacuum, such a trap is vital to prevent solvent vapors from getting into the pump oil, thereby ruining the lubrication and the vacuum created.
A cold trap can be constructed of either glass or steel; it need only be large enough to hold the solvent collected, and airtight so as not to ruin the vacuum with leaks. This cold trap is then cooled down with dry ice during vacuum evaporations to condense the solvent vapors in the trap.
The solvent recovered in the trap can be re-used in the given stage of the process from whence it came. I would not co-mingle recovered solvents from different stages.
For example, chloroform from the alkaloid extraction of the crops should be kept for that usage, and not be used for LSD crystallization, because it will also contain some ammonia and methanol. The recovery of ether, for example, from method 2 of lysergic acid production, poses a special problem. This problem is the formation of explosive peroxides in ether during storage. Ether containing water and alcohol, as would be the case for this recovered solvent, does not form much peroxide. There is a possibility that dry ether can be made free of peroxides by shaking the ether with some 5% ferrous sulfate (FeSO4) solution in water prior to distilling. Failure to do this may expose the operator to a fiery explosion during distillation.
Ice water flowing through the condenser, and an ice-chilled receiving flask, are required to get an efficient condensation of the ether during distillation. 11 Keeping Out Of Trouble 71 II Keeping Out Of Trouble The dangers of LSD manufacturing do not end with the possibility that the cooker may spill some of the stuff on himself and fry his brain. There is a much more malignant danger facing those who embark upon this course: Johnny Law. The conduit through which those shit-eating dogs travel to get to you is your associates. If you are cooking alone with no partners in crime, your safety has been impro

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