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Salvia divinorum is a very rare plant, being found in only a few ravine locations in the Sierra Mazateca mountains. The plant is easily propagated by cuttings, and during the past few decades it has made its way into numerous botanical gardens and private collections around the world. Virtually all of the Salvia divinorum in circulation has been vegetatively propagated from two parent clones of this species. The first specimen was collected by R. Gordon Wasson in 1962. A second, so called "palatable" strain was collected by Bret Blosser in 1991. The "palatable" variety is actually still quite bitter, although less so than the Wasson clone. There are a few other strains being maintained, some of which were grown from seed, but these are not in general circulation.
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ghttp://www.google.com/ Salvia divinorum is a perennial labiate used for curing and divination by the Mazatec Indians of Oaxaca, Mexico. The psychotropic effects the plant produces are compared to those of the other hallucinogens employed by the Mazatecs, the morning glory, Rivea corymbosa L., Hallier f. and the psilocybin-containing mushrooms.
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be distracted by other matters while the product spoils.
There are several alternate procedures for the extraction of the
amides from ergot. They all produce roughly similar results. This is
fortunate, as it allows the acid chemist to choose the materials used
based upon availability rather than being rigidly locked into using a
certain set of materials.
The first step in the extraction procedure, regardless of whether
ergot or seeds are being extracted, is a thorough grinding. A blender is
suitable for this job, and a coffee grinder may work as well if it gives a
fine grind. Once the crop has been ground up, it is immediately
vulnerable to attack by light and air, so as soon as it is ground it
should be wetted with the solvent chosen for use in the next step:
Defatting is a very important step in the isolation of pure alkaloid.
The fats and oils present in the crop must be removed because if they
were left in, a tenacious emulsion would form during the extraction of
the alkaloid, and you could forget about ever getting even close to a
pure amide extract. For all practical purposes, all that would be
extracted would be garbage.
Defatting can be done with any one of several very common and
easily available solvents. For a 200 pound crop, one can count on
using at least one, and possibly two 55 gallon drums of solvent. The
defatting can be done with either hexane, petroleum ether (not ethyl
ether) mineral spirits or naphtha. The preferred procedure for small
scale extractions is to put the ground-up, solvent-soaked crop into a
burette, and then keep dripping fresh solvent onto the top of the
material until the solvent coming out at the bottom of the burette does
not leave a grease stain on filter paper when the solvent dries. This is
easily scaled up for our 200 pound crop by replacing the burette with
clean pipes about 4 inches in diameter, and about 4 feet long, with
suitable valves and filters at the bottom to prevent everything from
falling out. (See Figure 1). When all the fats have been removed from
Extraction And Isolation Of
The Lysergic Acid Amides
the crop, the best procedure is to
evaporate the remaining defatting
solvent from the crop under a
vacuum. This is not practical for
a large crop, so letting the
remainder drip out of the bed
over a period of a few hours is
With the fats removed, the
ergot alkaloids can be extracted
from the crop. Note here the
word alkaloid. This is the key to
all variations of the extraction
procedure. There is a piperidine
nitrogen atom in the lysergic
these molecules that possesses
basic properties similar to ammonia and amines. This atom allows
the lysergic molecules to form salts with acids, and also causes the
solubility characteristics of the molecule to change depending upon
whether the molecule is in acid or basic solution. It further allows the
lysergic amides, including LSD, to form crystals from solution.
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